- BSc . 1998 Faculty of Chemical Engineering, Technion
- MSc. 2000 Faculty of Chemical Engineering, Technion
- Ph. D. 2004 Faculty of Chemical Engineering, Technion
- 2006- Assistant Prof., Faculty of Biomedical Engineering, Technion (tenured 2012)
- 2004-2006 Post-doc, Department of Pathology and Lab Medicine, University of California at Los Angeles
PuplicationsTo see the full list click >> https://weihs.net.technion.ac.il/publications/
- Naama Gal and Daphne Weihs, “Experimental Evidence of Strong Anomalous Diffusion in Living Cells”, Physical Review E81, 020903(R) (2010).
- Naama Gal and Daphne Weihs, “Intracellular mechanics and activity of breast cancer cells correlate with metastatic potential”, Cell Biochemistry and Biophysics63(3), 199-209 (2012).
- Naama Gal, Diana Goldstein, and Daphne Weihs, “Particle Tracking in Living Cells: A Review of the Mean Square Displacement Method and Beyond”, Rheologica Acta52(5), 425-443 (2013).
- Revital Kristal-Muscal, Liron Dvir, and Daphne Weihs, “Metastatic cancer cells tenaciously indent impenetrable, soft substrates”, New Journal of Physics15, 035022 (2013).
- Liron Dvir, Ronen Nissim, Martha Alvarez, and Daphne Weihs, “Quantitative measures to reveal coordinated cytoskeleton-nucleus reorganization during in vitro invasion of cancer cells”, New Journal of Physics17, 043010 (2015).
- Samer Toume, Amit Gefen, and Daphne Weihs, “Printable low-cost, sustained and dynamic cell stretching apparatus”, Journal of Biomechanics49, 1336-1339 (2016).
- Sonbula Massalha and Daphne Weihs, “Metastatic breast cancer cells adhere strongly on varying stiffness substrates, initially without adjusting their morphology” Biomechanics and Modeling in Mechanobiology16, 961-970 (2017).
- Yulia Merkher and Daphne Weihs, “Proximity of metastatic cells enhances their mechanobiological invasiveness“, Annals of Biomedical Engineering 45(6), 1399-1406 (2017).
- Martha B. Alvarez-Elizondo and Daphne Weihs, “Cell-gel mechanical interactions as an approach to rapidly and quantitatively reveal invasive subpopulations of metastatic cancer cells“, Tissue Engineering Part C: Methods23(3), 180-187 (2017).
Main Research Interests
Main research interests Application of cell biomechanics approaches to characterize and diagnose disease development. Focus on cancer development, prediction of metastasis formation in the body, personalized medicine matching of chemotherapy, immunotherapy and natural treatments. Novel approaches to prevent wound formation and accelerate healing.
- Real-time, high-resolution fluorescence microscopy with combined time-lapse.
- Particle tracking microrheology, Bio-microrheology
- Traction force microscopy for cell-substrate forces
- Various cell biology techniques (immunofluorescence, viability and proliferation, etc.).
- Laser tweezers for accurate force application and measurement in and on cells.
- Image processing for high-resolution particle tracking.
- The mechanical aspects of cancer development and progression in the body
- Prediction of metastatic cancer in the human body using personalized mechanobiology methods
- The correlation between mechanobiology of cancer and genotype or phenotype markers
- Development of methods to accelerate healing of wounds in the body
- Novel approaches to prevention of chronic wounds