Education:B.Sc. 1962 Agricultural and Civil Engineering, Technion-IITD.Sc. 1970 Biomedical Engineering, Technion-IIT Postdoctirate 1970 – 1973 Department of Bioengineering, University ofCalifornia at San Diego, La Jolla, California.Academic appointments:2008- Professor Emeritus, Faculty of Biomedical Engineering, Technion – I.I.T, Haifa, Israel.2005 Visiting Professor, Department of Biomedical Engineering, The Johns Hopkins Medical Institutions, Baltimore, Maryland.2004-2005 Visitting Professor, Institute of Bioengineering, University of Auckland, Auckland, New Zealand.2004 Research Associate, Harvard School of Public Health, Harvard University, Boston, Massachusette.2003-2004 Research Associate, Department of Biomedical Engineering, University of Pennsylvania, Philadelphia.1998-1999 Visiting Professor, Department of Biomedical Engineering, Faculty of Engineering, Tel-Aviv University, Tel-Aviv, Israel1998-2008 Holder, The Marcus Reiner Chair in Rheology1988-2008 Professor, Faculty of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel.1986 Visiting Professor, Section of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.1981 - 1988 Associate Professor, Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel.1981 - 1988 Associate Professor, Faculty of Mechanical Engineering, Technion - Israel Institute of Technology (Secondary Appointment), Haifa, Israel.1980 - 1981 Visiting Professor, Department of Biomechanics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan.1979 - 1980 Visiting Associate Professor, Department of Biomechanics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan.1973 - 1981 Senior Lecturer, Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel.1975 - 1979 Senior Lecturer, Faculty of Mechanical Engineering, Technion-Israel Institute of Technology (Secondary Appointment), Haifa, Israel.1970 – 1973 NIH Post-Doctoral Fellow, Department of AMES – Bioengineering, University of California at San Diego, La Jolla, California.Professor Lanir worked in industrial research and development until 1968. On completing post-doctoral training at the University of California, San Diego (1970-73), he joined the Department of Biomedical Engineering at the Technion-IIT in 1973, and served as its head from1974-75. He was appointed a Full Professor in 1988. During this period he was a Visiting Professor at Michigan State University from1979-81 and Johns Hopkins Hospital in 1986, and acted as a scientific consultant at the Weizmann Institute of Science from 1982-85. Since then he was a Visitting Scholar and Visitting Professor at University of Pennsylvania, Harvard University, University of California at Irvine, Auckland University and the Johns Hopkins Medical Institutes. Since 1998 Professor Lanir has held the Marcus Reiner Chair in Rheology. From 1990-1998 he was a member of the World Council on Biomechanics. Professor Lanir has been the coordinator of the undergraduate program in BME studies since its inception in 1996 till 2002. He is the coordinator of the Laboratory for the Mechanics and Function of Cells, Tissues and Organs.
Selected Publications- Kaimovitz B., Lanir Y., and Kassab G. S.: A Full 3-D Reconstruction of the Entire Porcine Coronary Vasculature. Am J Physiol Heart Circ Physiol. 299: H1064–H1076, 2010.- Algranati D, Kassab GS, Lanir Y.: Mechanisms of Myocardium - Coronary Vessel Interaction. Am J Physiol Heart Circ Physiol. 298: H861–H873, 2010.- Raz, E., and Lanir, Y.: Recruitment Viscoelasticity of the Tendon. J. Biomech. Eng. 131:111008 (2009).- Lokshin, O., Lanir, Y.: Micro and Macro Rheology of Planar Tissues.Biomaterials, 30: 3118–3127, 2009.- Huo, Y. Kaimovitz, B., Lanir, Y. Wischgoll, T., Hoffman, JEI., and Kassab, GS.: A Biophysical Model of Spatial Heterogeneity of Myocardial Flow, Biophysical Journal 96(10):4035-43, 2009.- Lanir, Y., Mechanisms of residual stress in soft tissues. J. Biomechanical Eng. 131(4): 044506, 2009.- Lokshin, O., and Lanir, Y.: Viscoelasticity and preconditioning of rat skin under uni-axial stretch: Micro-structural constitutive characterization. J. Biomechanical Eng 131(3): 031009, 2009.- Jacobs, J., Algranati, D., and Lanir, Y.: Lumped Flow Modeling in Dynamically Loaded Coronary Vessels. J. Biomechanical Eng 130: 054504, 2008.- Kaimovitz, B., Huo, Y., Lanir, Y., and Kassab, GS.: Diameter Asymmetry of Porcine Coronary Arterial Trees: Structural and Functional Implications. Am J Physiol Heart Circ Physiol 294: H714–H723, 2008.- Guo, X., Lanir, Y., and Kassab, G.S.: Effect of Osmolarity on the Zero-Stress State and Mechanical Properties of Aorta in Various Species. Am J Physiol Heart Circ Physiol. 293(4):H2328-34, 2007.- Wang, C., Garcia, M., Lu, X., Lanir, Y., and Kassab, G.S.: Three-Dimensional Mechanical Properties of Porcine Coronary Arteries: a Validated Two Layer Model. Am Physiol Heart Circ Physiol 291(3):H1200-9, 2006.- Kaimovitz, B., Lanir, Y., and Kassab, G S.: Large-Scale Geometric Reconstruction of the Porcine Arterial Vasculature Based on Detailed Anatomical Data. Annals of Biomedical Engineering, 33(11): 1517-1535, 2005.- Sverdlik, A. and Lanir, Y.: Time-Dependent Mechanical Behavior of Sheep Digital Tendons, Including the Effects of Preconditioning. ASME Trans. J. Biomechanical Eng. 124:78-84, 2002.- Lanir, Y., Lichtenstein, O. and Imanuel, O.: Optimal Design of Biaxial Tests for Structural Material Characterization of Flat Tissues. ASME Trans. J. Biomechanical Eng. 118:41-47, 1996.- Lanir Y., Hayam, G., Abovsky, M., Zlotnick, A.Y., Uretzky, G., Nevo, E. and Ben-Haim, S.A.: The Effect of Myocardial Swelling on the Residual Strain in the Left Ventricle of the Rat. Am. J. Physiol. 270:H1736-H1743, 1996.- Lanir, Y.: Plausibility of Structural Constitutive Equations for Swelling Tissues - Implications of the C-N and S-E Conditions. ASME Trans. J. Biomechanical Eng., 118:10-16, 1996.- Fibich, G., Lanir, Y. and Liron, N.: A Mathematical Model of Blood Flow in a Coronary Capillary. Am. J. Physiol. Heart Circ Physiol 265:H1829-H1840, 1993.- Lanir, Y.: Constitutive Equations for Fibrous Connective Tissues. J. Biomechanics 16:1 12,1983.
Main Research Interests
Field of research:Tissue Mechanics and Function; Coronary Circulation; Cell Micro-Rheology;Research interests:Our primary research activity is the basic and applied quantitative analysis of the mechanics and function of cells, tissues and organs. Theoretical and experimental studies range from cellular mechano-transduction, through the fundamental aspects of tissues' material properties, to pathophysiological processes. We are investigating the underlying morphological, mechanical, transport and physicochemical mechanisms, and their integration from the nano and micro scale into the overall macro behavior. Our studies of the coronary circulation focus on the interaction of blood flow with cardiac contraction, regulation of the coronary flow, analysis of pathophysiological cardiological events and of their diagnosis.Tissues' Micro-Structure and Mechanics Viscoelasticity ad Preconditioning of Connective Tissues Large Scale Simulation of the Coronary Circulation Cardiac Mechanics and Function. Cellular Micro-Rheology and Nano-Motion
Honors and Awards:1961: Bareli Prize for excellent scholarship1962: B.Sc. - Faculty of Agricultural Engineering - Cum Laude1982: Henri Gutwirth Research Award: Preconditioning in Collagen Fibers.1985: Henri Gutwirth Research Award: Experimental Investigation of theRheology of Soft Tissues.1992: The Lee Silver Friedman Award in Biomedical Engineering2003: The Richard Skalak 2002 Best Paper Award, The BioengineeringDevision, American Society of Mechanical Engineering.- American Society of Mechanical Engineering - Biomedical Engineering Society - International Society of Biomechanics - Israel Society of Medical and Biological Engineering - International Society of Biorheology - Cardiovascular System Dynamics Society